PRESENTATION  

        My name is Mihai Chirita and I am an University Professor with expertise in  biomaterials, at the University of Medicine and Pharmacy “Gr.T.Popa” University of Iasi, Romania. www.biomateriale.ro . I have also a second degree in nutrition.

        I have written many books related to biomaterials and natural systems. 

        My newest editorial appearance is a Biomolecule Treaty which contains 3 volumes and 1380 pages and is unique in the specialty literature in medical bioengineering. I mention that, in my family, I represent a second generation of hight degree specialists of protein and aminoacids science.

        The range of bio products that I propose to manufacture fall into the class of dietary supplements and sum up, both notions of cell medicine and amino acid therapy. 

        They are bio-innovative products, with biomimetic action, designed to act in a controlled manner in support of the cells of the body, in managing vital processes. There are combinations of amino acids and micronutrients and other biomolecules, designated to have a synergistic role, both in cellular metabolism and in the regulation of vital processes. 

 

        The current concept of antiaging is based on the administration of biomolecules. 

        This concept has captured an important segment of the food supplement market, however, there are too few products that have a real effect and not just a placebo. 

        The contents of the preparations existing on the market are metabolized on the gastrointestinal tract, absorbed and processed in the liver, the resulting products have unchecked systemic distribution. Practically there are useless preparations, which may be do  not harm but they have no useful therapeutic effect.

        These have adverse effects and can contribute to severe imbalances of the metabolic cycle. Pharmaceutical industry is based on drugs that mainly treat the symptoms and have side effects. The perpetuation and global expansion of this range of products is justified by revenue.

        The range of bio products patented  by me are the most advanced at the moment, does not present contraindications of administration and with these products I would treat myself. 

 

DESCRIPTION AND MOTIVATION 

        The hierarchy of organization of living systems comprises small and macro molecular substances, cellular organelles, cells, tissues and organs.

        All living organisms are made up of cells.

        The cell is the basic unit of life. It is the smallest entity that can exist in a living, independent system. The cells are products of a long evolution and have a complex internal order, which gives them the capacity for growth, development and reproduction, as well as a dynamic organization. The cells are in equilibrium relations with the external environment, have the capacity of self-regulation and adaptation to the variations of the environmental conditions, have a high degree of organization, which is maintained due to the fact that, from a thermodynamic point of view, they are an "open system" , that is, they have an energyconsuming structure on account of the external environment.

        The cell represents an open biological system, an assembly of different elements, interconnected structurally, spatially, functionally and temporally, which permanently changes with its external environment matter, energy and information. It has integrity, its own metabolism (exchange of substances and energy with the environment), capacity for selfregulation (exchange of information with the environment), self-preservation and selfreproduction.

         Life depends on the supply, in sufficient quantities, of four main elements: air (oxygen), water, macronutrients (proteins, fats and carbohydrates) and micronutrients (vitamins, minerals, certain amino acids and trace elements).

         Proteins are the essential components next to water, inorganic salts, lipids, carbohydrates, nucleic acids, vitamins and enzymes etc., of liquid and gelled materials in cells, in which take place intense physical-chemical interactions, under the name of life.

        The normal functioning of the body depends on what happens inside the cells of different types.

        The human body, in order to carry out its activity in good conditions, must receive a daily amount of energy and nutrients (proteins, carbohydrates, lipids, minerals, vitamins and water). They are provided through food intake. In addition to the energy needs, the body also needs nutrients (proteins, lipids, carbohydrates, minerals, water and vitamins), which are essential for maintaining life and carrying out its normal activity.

        The optimal functioning of cells is a prerequisite for health. 

        If the cells are in distress then the body becomes disordered and various pathologies appear. 

 

        Cellular medicine is a new scientific concept that explains that the main cause of today's most common chronic diseases, including various forms of cardiovascular disease, diabetes, cancer and others, is a chronic deficiency of vitamins, minerals, amino acids and other specific nutrients. Cellular medicine wants to define an optimal daily intake of specific micronutrients and macronutrients as a basic preventive measure for maintaining health and effective and safe control of many pathological conditions.

         The lack of micronutrients in the body does not give an alarm signal, as, for example, the lack of oxygen triggers the sensation of suffocation, the lack of water causes thirst and the lack of food causes hunger. The deficiency of vitamins and other essential nutrients, transporters of cellular bioenergy, do not give the body alarm signals.

         All vital processes in the body (circulation, respiration, excretion, muscle contraction, etc.) are performed at the expense of energy. Energy needs are the most important and the body seeks, above all, to satisfy them; when they are not satisfied, through exogenous input, the body uses its own tissues, which it burns to obtain the energy it needs.

         The main energy providers of the body are the calorific nutritional principles: lipids, carbohydrates and proteins, exo or endogenous in nature. Macronutrients contain energy stored in chemical bonds. This energy is released in the metabolic processes and stored in the form of macro-energy bonds in the ATP molecule, which represents the universal energy source, belonging to all living forms on Earth. ATP molecules are generated at the level of cellular metabolism, within the mitochondria, through the process of cellular respiration.

         It is estimated that a man produces and consumes his own weight in ATP every day.

         The most energy-consuming organs are the brain, heart, muscles and liver.

         To maintain vital functions, the body consumes a minimal amount of caloric energy, called basal metabolism (BM). Energy requirement (ER) is the daily energy expenditure, which must be covered by food consumption. The energy requirement varies widely, from one individual to another and even to the same person, depending on the physiological state and the adaptive demands induced by the environment. It should cover both basal metabolism and additional energy expenditure, of which the most important are those related to physical activity, thermoregulatory effort, specific dynamic action of foods (SDA) and physiological states.

         If certain elements cannot be brought into the body through exogenous sources, the use of dietary supplements is recommended.

         The selection of vitamins, minerals, amino acids and trace elements must be made on a scientific basis, from biomimetic considerations, adapting to each individual, as bioenergy providers for the multitude of cells that make up the human body.

         These deficiencies in nutrition and cell health recommendations are intended for everyone, regardless of age, both healthy people and patients. Cellular medicine outlines an optimal daily intake of specific nutrients, both as a preventive and therapeutic measure, as well as the slowing down of aging processes.

        Almost all people want to be immortal. Unfortunately, telomere is becoming shorter by cell division, and the information transmitted is increasingly different from the primary one. Can we do something in this direction? Do our products on the market help us?

        Medicines only seek to reduce the effects. 

        Most of the time, side effects do not immediately impress. The body reacts by seeking to adapt. This is not the way to go. 

        But I can provide cells with natural building, repair and stimulation materials. This pathway does not lead to immortality but to maintaining health and prolonging life.

        In the upper animals the amino acids are constituents of the proteins necessary for the growth and restoration of the tissues and precursors of many biomolecules such as: enzymes, hormones, some vitamins, etc. 

        Amino acid therapy or amino therapy, is a very new concept for the prevention, control and treatment of diseases, using only biomolecules. 

 

        My dietary supplements are all bio-innovative products, with biomimetic action, designed to act in a controlled manner in support of the cells of the body, in managing vital processes. There are combinations of amino acids and micronutrients and other biomolecules, designated to have a synergistic role, both in cellular metabolism and in the regulation of vital processes. 

        The products are for human health, can naturally heal or prevent and prolong the healthy life time. 

 

        I would like to work in this direction with specialists from China to include in the list of raw materials a series of natural plant or animal products known to have a content beneficial to human health. 

 

       Prof. univ.dr. Mihai Chirita

 

       If you have any interests please don't hesitate to contact the ISBE secretariat at xmtian@isbe-online.org.